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M9651001.TXT
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1996-03-30
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Document 1001
DOCN M9651001
TI Cyclospora cayetanensis infection in patients with and without AIDS:
biliary disease as another clinical manifestation.
DT 9505
AU Sifuentes-Osornio J; Porras-Cortes G; Bendall RP; Morales-Villarreal F;
Reyes-Teran G; Ruiz-Palacios GM; Department of Infectious Diseases,
Instituto Nacional de la; Nutricion Salvador Zubiran, Mexico City,
Mexico.
SO Clin Infect Dis. 1995 Nov;21(5):1092-7. Unique Identifier : AIDSLINE
MED/96125987
AB We describe patients with and without AIDS who had Cyclospora
cayetanensis infection; these patients were seen at a tertiary care
teaching hospital in Mexico City because of diarrheal disease. C.
cayetanensis was detected by examination of fresh fecal preparations and
acid-fast staining of fecal smears; the presence of other bacteria and
parasites was excluded by standard methods. Fecal specimens from 12
patients contained C. cayetanensis. The overall mean duration of illness
was 94 days. Seven of the 12 patients had AIDS; these patients presented
with more weight loss than did patients without AIDS (P = .04). The
patients with AIDS also tended to have a more prolonged illness. Two
patients with AIDS had biliary disease that resolved when they received
therapy with trimethoprim-sulfamethoxazole for cyclospora infection; the
excretion of oocysts also ceased. Our data confirm that C. cayetanensis
causes diarrhea in humans and a significant weight loss in patients with
AIDS. In addition, Cyclospora could be involved in biliary disease in
patients with AIDS.
DE Adult Aged Animal AIDS-Related Opportunistic
Infections/*COMPLICATIONS/*DIAGNOSIS/ PARASITOLOGY Biliary Tract
Diseases/*COMPLICATIONS/PARASITOLOGY/ ULTRASONOGRAPHY
Coccidia/ISOLATION & PURIF/PATHOGENICITY
Coccidiosis/*COMPLICATIONS/*DIAGNOSIS/PARASITOLOGY
Diarrhea/COMPLICATIONS/PARASITOLOGY Feces/PARASITOLOGY Female Human
Male Mexico Middle Age Trimethoprim-Sulfamethoxazole
Combination/THERAPEUTIC USE Weight Loss JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).